Stage 4 patient has majority of times received multiple treatment modalities previously. Both cancer and its treatment are morbid. Therefore, its of utmost importance to decipher the effective treatment plan which helps in maximising cancer control with minimum adverse effects Understanding treatment options for stage 4 cancer primarily involves a deep dive into the conventional methods that have been the backbone of oncology. These treatments aim to manage symptoms, control disease progression, and extend the quality of life, even in the most advanced stages of cancer. Surgery in stage 4 cancer is generally palliative; rarely curative, intended to relieve symptoms or reduce the burden of tumor masses that cause discomfort or functional problems. It can significantly enhance comfort and manage complications, such as obstructions or bleeding. Chemotherapy remains a fundamental treatment for stage 4 cancer, utilizing powerful drugs to target and kill rapidly dividing cancer cells. As a systemic treatment, chemotherapy is capable of reaching cancer cells at any site in the body, which makes it invaluable in cases where the cancer has spread to multiple locations. Despite its efficacy, the side effects can be demanding, and the treatment must be carefully tailored to the individual's health status and cancer type. Also, the patient might have already received some form of chemotherapy, cancer also acquires resistance to chemotherapy, it becomes essential to ascertain the appropriate drug so that actual cancer control can be achieved instead of just adding to the morbidity of chemotherapy Radiation therapy is another cornerstone of treatment, often used to shrink tumors and alleviate symptoms associated with advanced cancer, such as pain or pressure. This method can be particularly effective for targeting specific areas where cancer has spread, such as bones or the brain, providing significant relief and improving life quality. Targeted therapy offers a more precise approach by focusing on specific genetic pathways or mutations that are involved in the growth and spread of cancer. These treatments can potentially block the growth and spread of cancer by interfering with specific molecules ("targets") that are involved in the progression of the disease. Because targeted therapies are designed to more precisely identify and attack cancer cells while doing less damage to normal cells, they often have different side effects than chemotherapy. Targeted therapy is majorly expensive, therefore at AOHC we use Precision Oncology methods to identify such pathways and then choose the appropriate Targeted drugs which shall bring in results rather than just prescribing it blindly Immunotherapy has transformed the landscape of cancer treatment by boosting the body's immune system to fight cancer more effectively. It has proven particularly beneficial for types of cancer that were previously very difficult to treat at advanced stages. By enhancing the immune system's natural ability to combat cancer, immunotherapy has opened new avenues for extending survival and improving patient outcomes in stage 4 cancers. These conventional treatment options, while robust, are continually being refined and improved through ongoing research and clinical trials, ensuring that they remain at the forefront of the fight against advanced cancer.